Last Updated: 06/10/2025
Analysis of the ability of malaria antigen-specific CD4+ memory T cells and the suppressive mechanism by IL-27
Objectives
This study aims to clarify the control mechanism of immune memory T cells induced by malaria parasite infection using a mouse infection model.
Principal Institution
Principal Investigators / Focal Persons
Rationale and Abstract
It has been pointed out that in malaria endemic areas, immune memory in infected individuals is difficult to maintain. In particular, it has been revealed that the cytokine IL-27 has a regulatory role in malaria immune memory, and this study will elucidate its control mechanism. This is basic research for immune control of malaria and vaccine development.
External reference
Themes
Date
Apr 2025 — Mar 2028
Total Project Funding
$30,892
Funding Details
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